It's a moment Neve Campbell will never forget. There she was on the set of "Drowning Mona" when co-star Jamie Lee Curtis stormed over, seemingly ready to pick a fight. "You know how they say I'm the new Scream Queen because of the 'Scream' movies? Well, on the first day of shooting 'Mona,' Jamie Lee comes over to me, looking really mad," recalls Campbell, 26. "I was like, "Wow, what did I do?" Then she smiles and says, "I want my crown back."

Campbell laughs at the memory. "She's an incredible person and because she has such fond feelings about her 'Halloween' movies, it gave me a better outlook about what' Scream' has done for me."

At the moment, Campbell feels all screamed out. Even though "Scream 3" exceeded everyone's expectations by earning $34.7 million in its opening weekend, the actress insists she's been menaced by her last hooded killer. "It's really the end," she says during an interview at Manhattan's Essex House Hotel. "I'm sad because I had such fun making the movies and because of all the friends I've made through them. But it's also a relief. There wasn't too much more I could do with that character."

Ironically, Campbell's other series - Fox's popular "Party of Five"- is also coming to a close. The hour¬-long drama about a family of siblings orphaned after their parent's car ¬crash is going off the air at the end of the season. "My contract was up after this season and I don't think I would have been back," says Campbell. "I've worked 15 hours a day for six years as Julia. I've spent more time being Julia than I have myself, which is scary. But it's definitely a bittersweet time for me." Although Campbell refuses to comment on the show's final episode, which will air this spring, she promises it will be something special.

"I keep suggesting to Fox that the entire family gets run over by a huge Mack truck," she teases. "Wouldn't that be great? I know it's a little bit on the depressing side, but, hey, the show started when our parents were killed in a drunk-driving accident. I think we should keep with the sadness until the end.' Campbell might have a bit of a dour image thanks to "Party of Five" and the "Scream" movies but with "Drowning Mona," she sets out to change that.

The black comedy, which has been dubbed a white-trash version of "Murder on the Orient Express," centers on a small-town sheriff (Danny DeVito) determined to catch the killer of the much-hated Mona Dearly (Bette Midler). Campbell, along with Casey Affleck and Jamie Lee Curtis, is one of the prime suspects. "I was terrified of the movie," Campbell says of one of her first forays into comedy. "It's always scary to try new things, but you want to pull it off. The character is ridiculous. The film is absurd. I decided to be as ridiculous as I could."

Campbell, it turns out, can be pretty ridiculous. The actress, whose loud laugh once earned her the nickname "Foghorn," has the chops to pull off over-the-top comedy. "I think Neve is a comic genius," says "Drowning Mona" director Nick Gomez. "Her timing is impeccable. She made all of us laugh." Now that she's wrapped up work on "Mona," Scream 3" and "Party of Five," Campbell is ready to take a break from acting, at least for a little while.

"I've been working since l was a teen, so I didn't have time for a personal life," says the Toronto¬ born actress who broke into show business at the age of 15 when she landed a role in a Toronto production of "The Phantom of the Opera." "But I do like good conversations. I like crafts. I want to learn how to play the guitar and speak Spanish. I want to do a bunch of things." One thing Campbell won't be doing is mulling over a return to the terror movie genre. Despite the fact that she netted $7 million to star in the last installment of "Scream," she swears she'll never shriek again.

"I figure when I'm 50 and broke, maybe I'll want to do another one," she laughs. "As in "Return to Scream." Maybe the deal is my character Sidney has been in an insane asylum for all these years. She breaks out and becomes a killer herself. What do you think?"